In 2261, the Vorlons join the Shadow War, but their tactics become a concern for the alliance when the Vorlons begin destroying entire planets which they deem to have been "influenced" by the Shadows. Disturbed by this turn of events, Babylon 5 recruits several other powerful and ancient races (the First Ones) to their cause, against both the Shadows and the Vorlons. Captain John Sheridan returns to the station after escaping from Z'ha'dum, but at a price: barring illness or injury, he has only 20 years left to live. He is accompanied by a mysterious alien named Lorien who claims to be the oldest sentient being in the galaxy.
Hours before Sheridan's return, Garibaldi is rescued and returned to the station, in rather dubious circumstances. He is markedly more paranoid and suspicious of other alien races and of Sheridan than he was before.
Centauri Emperor Cartagia forges a relationship with the Shadows. Londo Mollari engineers the assassination of Cartagia and repudiates his agreement with the Shadows. Londo kills Mr. Morden and destroys the Shadow vessels based on the Centauri homeworld, in an attempt to save his planet from destruction by the Vorlons. Aided by the other ancient races, and several younger ones, Sheridan lures both the Vorlons and the Shadows into an immense battle, during which the Vorlons and Shadows reveal that they have been left as guardians of the younger races, but due to philosophical differences, ended up using them as pawns in their endless wars throughout the ages. The younger races reject their continued interference, and the Vorlons and Shadows, along with the remaining First Ones, agree to depart the galaxy forever.
After the Shadows are defeated Garibaldi leaves his post as security chief and works on his own as a "provider of information". He begins working for one William Edgars, a Mars Tycoon, who is married to Garibaldi's former love. While he works ever closer with Edgars, he becomes increasingly aggressive towards Sheridan and eventually leaves Babylon 5.
Minbar is gripped by a brief civil war between the Warrior and Religious castes. Delenn secretly meets with Neroon of the Warrior caste and convinces him that neither side can be allowed to win. She tells him that she will undergo a ritual wherein she will be willing to sacrifice herself, but will stop the ritual before she actually dies. When Neroon sees that she actually intends to go through the entire ritual, he rescues her and sacrifices himself instead, declaring that, although he was born Warrior, in his heart he is Religious.
As part of the ongoing conflict between Earth and Babylon 5, Garibaldi eventually betrays Sheridan and arranges his capture in order to gain Edgars' trust and learn his plans. Garibaldi later learns that Edgars created a virus that is dangerous to only telepaths. It is then revealed, that Garibaldi was actually abducted by the Psi-Corps at the end of Season 3 and re-programmed by Bester to provide information to him at the right time. Bester releases Garibaldi of his programming, and allows him to remember everything he has done since being kidnapped. Edgars is killed and his wife disappears, but is reunited with Garibaldi after the end of the war. Garibaldi helps free Sheridan and return him to the campaign to free Earth. An alliance led by Babylon 5 frees Earth from totalitarian rule by President Clark in a short but bloody war. This culminates in Clark's suicide and the restoration of democratic government. Mars is granted full independence, and Sheridan agrees to resign his commission. The League of Non-Aligned Worlds is dissolved and reformed into the Interstellar Alliance, with Sheridan elected as its first President and continuing his command of the Rangers, who are to act as a galactic equivalent of United Nations peacekeepers.
In the season finale, the events of 100, 500, 1000, and one million years into the future are shown, depicting Babylon 5's lasting influence throughout history. Amongst the events shown are the political aftermath of the 2261 civil war, a subsequent nuclear war on Earth involving a new totalitarian government in the year AD 2762, the resulting fall of Earth into a pre-industrial society, the loss and restoration of humanity's knowledge of space travel, and the final evolution of mankind into energy beings similar to the Vorlons, after which Earth's sun goes nova.
主演:冈·纳缇萨勘·差洛特,Nice Boripat Jamsat,塔纳克里特·塔拉索蓬,Dech Narongdet Rungarun,贾卡林·普里帕特,Nueng Malys Choeysobhon,坎塔彭·措姆普潘,威·维瑟缇,沙玛·帕亚卡荣,纳帕斯萨科恩·米代姆
主演:邝玲玲,珙恩娜帕·瑟塔拉塔那彭,玛丽琳·凯特·甘能,帕斯威奇·布拉纳努特,妮莎春·唐苏努恩,坦查诺克·优塔善西里,苏珀·臣查罗恩,阿披南·普拉瑟瓦塔纳坤,玛郁琳·彭普潘,提达露·帕鲁彤,佩拉克里特·帕查拉布纳亚基特,肯帕莎·斯莉苏卡化,克里特坎·普拉西特潘尼
主演:萨朋·阿萨瓦蒙空,萨林·朗那基特,西瓦功·勒楚戳,塔纳通·詹塔沃拉甘,塔纳本·吉塔澜,大卫·阿萨瓦纳德,塔尼·甘莫塔拉侬,Koi Tarika Thidathit
主演:梅塔文·欧帕西安卡琼,札玲朋·尊克迪,提娜丽·维拉瓦诺丹,芭莉雅皮·余
主演:内详
主演:基莉·霍斯,弗莱迪·海默,大卫·丹席克,莎罗姆·布龙-富兰克,杰拉尔德·基德,德文·特雷尔,吉娜·格申,Ibraim Cândido,奥罗拉·玛丽恩,埃利·哈达德,凯文·基尔南-莫洛伊,Soroush Helali,小弗洛林·皮尔斯齐,Ino Badanjak,亚历山大·亚岑科,Ali Fardi,杰克·达文波特,阿兰·戴尔,Mohamed Chahrour,Chike Chan
主演:梅塔文·欧帕西安卡琼,札玲朋·尊克迪,提娜丽·维拉瓦诺丹,芭莉雅皮·余
主演:卢克·纽伯里,大卫·沃姆斯利,哈丽特·肯斯,肯内斯·库兰汉姆,斯蒂夫·艾弗茨,艾米莉·贝文
主演:梅兰妮·斯科洛凡诺,格伦·古尔德,史蒂文·奥格,大卫·詹姆斯·艾略特,Romy Weltman,CM朋克,Andy McQueen,Jimmy MacKinley,Amy Rivard
主演:安东尼·布伊塞雷,普威·丹萨优,普鲁迪猜·鲁艾富潘特,Boom Saharat Thiempan,苏查妲·颂潘,瓦西塔·赫尔梅瑙,Obey Pun
主演:李·佩斯,杰瑞德·哈里斯,卢洛·贝尔,皮鲁·埃斯贝克,特洛伊·科特苏尔,切莉·琼斯,布兰登·P·贝尔,劳拉·布林,泰伦斯·曼,金宝·张,阿尔弗雷德·伊诺奇,艾略特·科万,Sasha Behar,克拉克·彼得斯,卡罗莱娜·美恩,Antony Bunsee,布莱恩·博维尔,里斯·谢尔史密斯,Vanessa Ifediora,库珀·卡特,金·阿迪斯,乔格·尼可洛夫,阿卜杜勒·阿尔沙瑞夫
主演:布鲁斯·巴克林纳,Michael O'Hare,克劳迪亚·克里斯蒂安,Jerry Doyle,米拉·福兰
主演:Bruce Boxleitner,Michael O'Hare,Claudia Christian,Jerry Doyle,Mira Furlan
主演:Bruce Boxleitner,Michael O'Hare,Claudia Christian,Jerry Doyle,Mira Furlan,Richard Biggs,Andrea Thompson,Bill Mumy,Jason Carter,Tracy Scoggins,Stephen Furst,Patricia Tallman,Peter Jurasik
主演:Bruce Boxleitner,Michael O'Hare,Claudia Christian,Jerry Doyle,Mira Furlan,Richard Biggs,Andrea Thompson,Bill Mumy,Jason Carter,Tracy Scoggins,Stephen Furst,Patricia Tallman,Peter Jurasik,Andreas Katsulas,Jeff Conaway,Robert Rusler
主演:Jerry Doyle,Mira Furlan,Claudia Christian
主演:Kelly Hu,Bruce Boxleitner,Kevin Michael Richardson,Jim Cummings,Keith Szarabajka
主演:Joe Lando,Claudia Christian,Cooper Harris
主演:Mirjana Jokovic,Mira Furlan,Adrian Ghio
主演:Casper Van Dien,Bruce Boxleitner,Ernest Borgnine
主演:Bruce Boxleitner,Rhett Giles,Jeff Denton
主演:李锦梅,黄文永,陈泰铭,成建辉,林倩萍
主演:Bruce Boxleitner,Michael O'Hare,Claudia Christian,Jerry Doyle,Mira Furlan
主演:约翰·肖,凯文·沃特利,克莱尔·霍尔曼,詹姆斯·格劳特,菲利斯·洛根
主演:杰瑞·宋飞,茱莉亚·路易斯-德瑞弗斯,迈克尔·理查兹,杰森·亚历山大
主演:理查德·布基,布鲁斯·A·扬,加雷特·马加特,斯科特·哈文
主演:约翰·普莱舍,冈本玉二,克里夫顿·戴维斯,迈克尔·佩纳,神奈川宏幸,Yanic·Truesdale,巴里·佩珀,罗伯特·拉萨多,伊安·崔西,维努斯·特雷佐,劳尔·特鲁希洛,理查德·泰森,加里·切克,本兹·安托万,艾伦·坡尔,加布里埃尔·米勒,马尔科姆·斯图尔特,乌多·基尔,埃里克·李塞德,沃尔顿·戈金斯,贾森·加里-斯坦福德,里昂·拉瑟姆,迈克尔·科普萨,斯蒂夫·巴西奇,萨姆·索尔沃,胡凯莉,卡万·史密斯,杰萨琳·吉尔西格,扎克·沃德,莫莉·帕克,鲍勃·弗雷泽,凯特·霍吉,史葛·麦克尼尔,塔玛拉·布劳恩,
主演:伊万·麦克格雷格,凯文·卡罗尔,乔治·克鲁尼,布里奇特·霍夫曼,安东尼·爱德华兹,雪莉·斯蒂琳费尔德,朱丽安娜·,斯科特·哈文
主演:Anthony·De·Longis,伊安·崔西,肖恩·卡梅伦·迈克尔,刘艺,哈基姆·凯-卡西姆,莫尔纳·维瑟,韦恩·罗布森,Andrew·Scorer,罗伯·斯特尔特,埃曼纽尔·施莱琪,罗宾·邓恩,Candice·Hillebrand,穆赛塔·万德,约翰·卡森,凯文·吉宾维尔,劳伦斯·贝恩,泽恩·格斯纳,萨布丽娜·格德维奇,加温·桑福德,Monika·Schnarre,范·弗洛伦斯,Gérard·Rudolf,Jacqueline·Collen,Kevin·Smith,Mariah·Shirley,莉莎·
主演:布莱恩·科兰斯顿,茱莉亚·路易斯-德瑞弗斯,迈克尔·理查兹,鲍勃·奥登科克,杰森·亚历山大,韦恩·奈特,杰瑞·宋飞
主演:詹妮弗·安妮斯顿,柯特妮·考克斯,丽莎·库卓,马特·勒布朗,马修·派瑞,大卫·休默
主演:大卫·杜楚尼,吉莲·安德森,米彻·佩勒吉,威廉·B·戴维斯,布莱恩·汤普森,史蒂文·威廉姆斯,劳瑞·侯登,莫里斯·潘迟,布雷丹·贝塞尔
主演:杰里·奥尔巴赫,本杰明·布拉特,埃帕莎·默克森,萨姆·沃特森,凯莉·洛维,Steven Hill
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